Antibodies Used to Detect Breast Cancer Cells- in Paraffin Embedded Sections?
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Breastfeeding and Reduced Breast Cancer Risk
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One Comment on “Antibodies Used to Detect Breast Cancer Cells- in Paraffin Embedded Sections?”
Paraffin section of what tissue?
In lymph nodes, cytokeratins can identify metastatic epithelial cells.
In breast tissue, overexpression of some antigens is common, but there is no universal marker.
Her-2/neu is targeted because there is a specific therapy (Herceptin).
Cyclin D1 and p53 are overexpressed in some tumors.
There are a variety of antibodies to each of these proteins.